Perhaps I am not a power user , but I am very happy with Linux Mint 11
(Katya) ,but so I am with Lubuntu 10.4,which I use (dual boot) on the same
desktop PC and also on an old P4 -512MB laptop and an Asus eeePC901 .
So far I have not have had 'any' problems with any of the above Linux
installations.
Recently I did run Ubuntu 11.10 live on the desktop PC and I am impressed.
Possibly I shall replace the Lubuntu 10.4 ( on the desktop PC) with Ubuntu
12.4 (LTS) .........wait and see first.