Currently I have 20 add-ons. Not all are enabled. I know that some
people run a lot more than that. I can see problems cropping up,
especially after add on updates, that people may not notice for days or
weeks. It would be a bit of a pain to disable all add-ons and later
enable then again, remembering which were initially disabled.
Acknowledging the fact that they may well have to be enabled one or a
few at a time to troubleshoot. but the possibility to limit the problem
directly to the Firefox program and not something in the operating
system is a very handy tool.