I don't think that Skype is Mono based. It is proprietary software with its
own P2P networking based on Kazaa from which it sprung. The reason why I
think that it is not written using .NET or Mono is that it has to be able to
run on many platforms from Linux, Windows, OS/X to mobile devices. Also, I
have Skype installed and all traces of Mono have been removed from my
system.

Congratulations on your success at removing Mono. I know that you will feel
better for it. Maybe its status will be clarified some day.